Polycaprolactone fiber-based bovine dendritic cell development and three- dimensional culture in vitro

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F23%3A43923810" target="_blank" >RIV/62156489:43210/23:43923810 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.55251/jmbfs.10304" target="_blank" >https://doi.org/10.55251/jmbfs.10304</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.55251/jmbfs.10304" target="_blank" >10.55251/jmbfs.10304</a>

Result language

angličtina

Original language name

Polycaprolactone fiber-based bovine dendritic cell development and three- dimensional culture in vitro

Original language description

Two-dimensional (2D) cell culture systems are normally used for in vitro experiments. These systems have some drawbacks which affect results of in vitro experiments because cultured cells have different morphology and physiological properties comparing to in vivo models. Therefore, there are current technique to develop three-dimensional (3D) cell culture systems which are closer to the environment in real tissues. In our study, we used polycaprolactone fiber scaffold for culture of bovine monocytes to develop dendritic cells (DCs) from those cells. Cultured monocytes in the polycaprolactone nanofiber scaffold differentiated to DCs. The differentiated DCs showed a 3D structure in the scaffold. These results suggest that this method is suitable for the development of DCs in a manner of three-dimension. These methods are perspective for bovine cell culture and has advantages compare to conventional 2D culture systems.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10606 - Microbiology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Microbiology, Biotechnology and Food Sciences

ISSN

1338-5178

e-ISSN

1338-5178

Volume of the periodical

13

Issue of the periodical within the volume

2

Country of publishing house

SK - SLOVAKIA

Number of pages

4

Pages from-to

"e10304"

UT code for WoS article

001021634100001

EID of the result in the Scopus database

2-s2.0-85173787188