Melanoma treatment: from conventional to nanotechnology
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43410%2F18%3A43913940" target="_blank" >RIV/62156489:43410/18:43913940 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1007/s00432-018-2726-1" target="_blank" >https://doi.org/10.1007/s00432-018-2726-1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00432-018-2726-1" target="_blank" >10.1007/s00432-018-2726-1</a>
Alternative languages
Result language
angličtina
Original language name
Melanoma treatment: from conventional to nanotechnology
Original language description
Introduction: Melanoma is the most serious form of skin cancer causing most of the skin cancer-related deaths. The incidence of melanoma has risen so dramatically over past few years that no other solid or blood malignancy comes close to it in terms of increased incidence. The main problem associated with the treatment of melanoma is low response rate to the existing treatment modalities, which in turn is due to the incomplete response by chemotherapeutic agents and inherent resistance of melanoma cells. Materials and Methods: Conventional therapeutic strategies, as well as, recent literature on melanoma have been thoroughly studied. This review summarizes the base of anti-melanoma treatment with conventional chemotherapeutic drugs, followed by an account of recent studies which explored the potential of nanotechnology and newer strategies and agents in melanoma treatment. Conclusion: Although melanoma is curable if detected in its early localized form, metastatic melanoma continues to be a therapeutic challenge. Metastatic melanoma has a very poor prognosis and conventional therapies have not improved the outcomes of the treatment so far. For this reason, newer combinations of anti-melanoma drugs and newer strategies utilizing nanotechnology have been constantly explored.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30204 - Oncology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Cancer Research and Clinical Oncology
ISSN
0171-5216
e-ISSN
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Volume of the periodical
144
Issue of the periodical within the volume
12
Country of publishing house
DE - GERMANY
Number of pages
20
Pages from-to
2283-2302
UT code for WoS article
000450850800001
EID of the result in the Scopus database
2-s2.0-85051286601