Structure, genome, infection cycle and clinical manifestations associated with Human Papillomavirus
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43410%2F19%3A43916145" target="_blank" >RIV/62156489:43410/19:43916145 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.2174/1389201020666190802115722" target="_blank" >http://dx.doi.org/10.2174/1389201020666190802115722</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2174/1389201020666190802115722" target="_blank" >10.2174/1389201020666190802115722</a>
Alternative languages
Result language
angličtina
Original language name
Structure, genome, infection cycle and clinical manifestations associated with Human Papillomavirus
Original language description
A small, non-enveloped, obligatory parasite, Human papillomavirus (HPV) is known to be the cause of a range of malignancies. These entail benign infections like genital warts as well as malignant, life threatening conditions such as cervical cancer. Since a very high mortality rate is associated with HPV caused cancers (cervical cancer being 2nd leading cause of death caused due to cancer among women globally), there is an escalating need to understand and search for ways to combat such medical conditions. Under the same light, the given article provides an insight into the world of this versatile pathogen. Distinct aspects related to HPV have been discussed here. Emphasis has been laid upon the composition, function and assembly of capsid proteins (structural studies) and various genetic elements and their gene products (genomic studies). An essence of the mechanism behind development of persistent infection and modes responsible for transmission of the infectious particles has been briefly covered. Finally, the review outlines various infections and diseases caused by HPV with major focus on their clinical and histological manifestations.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Current Pharmaceutical Biotechnology
ISSN
1389-2010
e-ISSN
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Volume of the periodical
20
Issue of the periodical within the volume
15
Country of publishing house
AE - UNITED ARAB EMIRATES
Number of pages
21
Pages from-to
1260-1280
UT code for WoS article
000498856100003
EID of the result in the Scopus database
2-s2.0-85075509229