Unlocking nature’s pharmacy: diversity of medicinal properties and mycochemicals in the family Hymenochaetaceae (Agaricomycetes, Basidiomycota)

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43410%2F24%3A43926095" target="_blank" >RIV/62156489:43410/24:43926095 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.5943/mycosphere/15/1/27" target="_blank" >https://doi.org/10.5943/mycosphere/15/1/27</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5943/mycosphere/15/1/27" target="_blank" >10.5943/mycosphere/15/1/27</a>

Result language

angličtina

Original language name

Unlocking nature’s pharmacy: diversity of medicinal properties and mycochemicals in the family Hymenochaetaceae (Agaricomycetes, Basidiomycota)

Original language description

Hymenochaetaceae is a large and noteworthy family of macrobasidiomycetes predominantly growing on woody plants. Several Hymenochaetaceae members have a long history of recognition in traditional medicine and modern pharmacological studies have demonstrated their therapeutic properties. This review comprehensively surveys the studies on biological activities and mycochemical compounds reported from the Hymenochaetaceae species so far. There are 124 potential species from 27 genera in Hymenochaetaceae with at least one bioactive metabolite and/or biological property. A diverse range of metabolites were found (ca. 500 compounds) classified mainly into terpenoids, styrylpyrones, steroids, phenolics, polysaccharides, and other compounds. Numerous novel sesquiterpenoids, triterpenoids, steroids, and styrylpyrones have been isolated from the family. Medicinal properties cover a range of about 100 types of bioactivities, more predominantly antioxidant, antitumor, antidiabetic, immunomodulatory, anti-inflammatory, antibacterial, and antifungal effects. The role of Hymenochaetaceae members in aesthetic medicine is also discussed. Molecular phylogenetic reconstructions reveal that the medicinal species are distributed in 27 monophyletic clades, and 20 medicinal species are types of their respective genera (generic types). So far most of medicinal Hymenochaetaceae species are shown to be distributed in Asia, particularly in China. Considering the drawbacks imposed by improper characterization of Hymenochaetaceae isolates in biomedical studies, general recommendations are given with the aim of encouraging greater focus on accurately identifying the medicinal fungal species.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10612 - Mycology

Project

<a href="/en/project/EF15_003%2F0000453" target="_blank" >EF15_003/0000453: Phytophthora Research Centre</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Mycosphere

ISSN

2077-7000

e-ISSN

2077-7019

Volume of the periodical

15

Issue of the periodical within the volume

1

Country of publishing house

CN - CHINA

Number of pages

92

Pages from-to

6347-6438

UT code for WoS article

001375812700001

EID of the result in the Scopus database

2-s2.0-85214562963