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Introduction to long noncoding RNA

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43410%2F25%3A43926672" target="_blank" >RIV/62156489:43410/25:43926672 - isvavai.cz</a>

  • Result on the web

    <a href="https://doi.org/10.1016/B978-0-443-21784-5.00011-3" target="_blank" >https://doi.org/10.1016/B978-0-443-21784-5.00011-3</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/B978-0-443-21784-5.00011-3" target="_blank" >10.1016/B978-0-443-21784-5.00011-3</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Introduction to long noncoding RNA

  • Original language description

    Research from several sources led to one of the most important findings in population genetics. They demonstrated how the size of the breeding population within a species affects natural selection&apos;s capacity to eliminate marginally harmful mutations. The greater the population size, the more adept natural selection is at spotting and removing marginally harmful mutations. The effective population size is much lower than the total population due to specific population dynamics factors. In fact, there is an inverse linear relationship between the size of the effective population and the degree of mutational harm required for natural selection to successfully remove a mutation from a population. Genetic drift alone will cause certain neutral and marginally harmful mutations to become fixed in the absence of selection pressure. It&apos;s crucial to understand that this relationship holds true for mutations that are only marginally helpful as well. Specifically, there is an inverse relationship between the effective population size and the level of benefit required for a mutation to be effectively chosen for by natural selection. Because of this, it is crucial to consider how a genetic modification impacts the organism&apos;s fitness and whether, given the size of the population, selection might influence this change in a positive or negative way. In the early and middle of the first decade of the 21st century, global transcriptomic analyses which aimed to better define the proteomeunveiled a novel surprise and posed a challenge to the conventional understanding of genetic information: the majority of the genomes of plants and animals are dynamically transcribed into longer RNAs with little to no potential to code for proteins. The majority of the transcriptome products produced by eukaryotic transcription lack the ability to code for proteins. The misclassification of noncoding RNAs as &quot;useless&quot; has largely contributed to the delay in our understanding of their functional activities. Despite not being able to convert into proteins, noncoding RNAs (ncRNAs) are nevertheless crucial for plant growth, development, and response to abiotic stress. Diverging in both biogenesis pathways and functional roles, noncoding. The unearthing of ncRNA has sparked a revolution in comprehending the intricacy and multiplicity of gene regulation within plants. Amidst the sundry ncRNA classes, one captivating and pivotal group has emerged: transposable element-derived noncoding RNAs(TE-derived ncRNAs).

  • Czech name

  • Czech description

Classification

  • Type

    C - Chapter in a specialist book

  • CEP classification

  • OECD FORD branch

    40101 - Agriculture

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2025

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Book/collection name

    Non-coding RNA in Plants: Modulation and Stress Responses

  • ISBN

    978-0-443-21784-5

  • Number of pages of the result

    12

  • Pages from-to

    1-12

  • Number of pages of the book

    358

  • Publisher name

    Elsevier Science Inc.

  • Place of publication

    New York

  • UT code for WoS chapter