A new HpaII PCR-RFLP within the porcine receptor (PRLR) gene and study of its effect on litter size and number of teats

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A_____%2F02%3A23300003" target="_blank" >RIV/62156489:_____/02:23300003 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

A new HpaII PCR-RFLP within the porcine receptor (PRLR) gene and study of its effect on litter size and number of teats

Original language description

DNA polymorphism of the porcine prolactin receptor gene (PRLR) was investigated and used to study its effect on litter size and number of teats in pigs. By means of PRLR gene sequence homology in pig, human and other species, primers were designed for PCamplification within 5´ unknown (to date) part of the prolactin receptor gene in pigs. In this part of the gene, a new polymorphism with HpaII restriction endonuclease was detected. AluI polymorphism described before and our new HpaII polymorphism were used to study the associations with reproduction traits. Statistical analysis of 1020 litters showed that AluI locus was associated with litter size mainly in Landrace and affected the first parities, while HpaII locus of the gene was associated with thesame traits in Landrace and Large White and mainly affected numbers of weaned of pigs. The magnitude of the effect varied by population with the effects exceeding 2 pigs in Landrace line and 1 pig per litter in Large White populations.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

<a href="/en/project/GA523%2F99%2F0842" target="_blank" >GA523/99/0842: Detailed mapping of QTLs in the pig by means of microsatellites and through comparative positional candidate gene approach</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2002

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Animal Breeding and Genetics

ISSN

0931-2668

e-ISSN

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Volume of the periodical

119

Issue of the periodical within the volume

1

Country of publishing house

GE - GEORGIA

Number of pages

7

Pages from-to

57-63

UT code for WoS article

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EID of the result in the Scopus database

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