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Clinical evaluation of medetomidine-opioid agonists, -partial agonists and -mixed agonist/antagonists combination for anesthesia premedication in the dog

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F03%3A00000382" target="_blank" >RIV/62157124:16170/03:00000382 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Clinical evaluation of medetomidine-opioid agonists, -partial agonists and -mixed agonist/antagonists combination for anesthesia premedication in the dog

  • Original language description

    The goal of the study is to emphasise clinically significant properties of medetomidine - opioids combinations. Total of 90 dogs were included to the study, in which various painful procedures had been performed. Dogs were divided into three groups. In the FEN group medetomidine 0.01 mg/kg (n=30) had been given with fentanyl 0.01 mg/kg bolus following by 0.01 mg/kg/hr infusion. The BUT group (n=30) presented combination of medetomidin 0.01 mg/kg with butorphanol 0.2 mg/kg bolus only. The BUP group (n=30) had been given medetomidine 0.01 mg/kg with buprenorphine 0.01 mg/kg. All combinations were used as a bolus mixed in one syringe. Anesthesia induction had been facilitate by propofol administration and then maintained by O<sub>2<sub>/N<sub>2<sub>O/halothane inhalation. Insufficient depth of anesthesia was solved by propofol readministration. As main criteria, the level of sedation, initiative dose of propofol, as well as the need of its readministration had been observed. Furth

  • Czech name

    Klinické zhodnocení kombinace medetomidinu-opioidního agonisty, -parciálního agonisty a agonisty/antagonisty pro premedikaci celkové anestezie u psů

  • Czech description

    Cílem studie bylo zhodnotit klinicky významné účinky kombinace medetomidinu s opioidy - s butorfanolem, buprenorfinem nebo fentanylem. Hodnocenými kritérii byla úroveň sedace po premedikaci, množství propofolu pro indukci a dávka inhalačních anestetik pro vedení anestezie a změna vitálních parametrů v průběhu anestezie. nejlepší sedaci navozovala kombinace s fentanylem, při níž bylo zároveň potřebné i nejmenší množství propofolu pro indukci.

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    FP - Other medical fields

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2003

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    8th World Congress of Veterinary Anesthesia

  • ISBN

    5400-5166

  • ISSN

  • e-ISSN

  • Number of pages

    1

  • Pages from-to

    138

  • Publisher name

    University of Tennessee

  • Place of publication

    Knoxville, Tennessee, USA

  • Event location

    Knoxville, Tennessee, USA

  • Event date

    Sep 16, 2003

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article