Clinical evaluation of medetomidine-opioid agonists, -partial agonists and -mixed agonist/antagonists combination for anesthesia premedication in the dog

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F03%3A00000382" target="_blank" >RIV/62157124:16170/03:00000382 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Clinical evaluation of medetomidine-opioid agonists, -partial agonists and -mixed agonist/antagonists combination for anesthesia premedication in the dog

Original language description

The goal of the study is to emphasise clinically significant properties of medetomidine - opioids combinations. Total of 90 dogs were included to the study, in which various painful procedures had been performed. Dogs were divided into three groups. In the FEN group medetomidine 0.01 mg/kg (n=30) had been given with fentanyl 0.01 mg/kg bolus following by 0.01 mg/kg/hr infusion. The BUT group (n=30) presented combination of medetomidin 0.01 mg/kg with butorphanol 0.2 mg/kg bolus only. The BUP group (n=30) had been given medetomidine 0.01 mg/kg with buprenorphine 0.01 mg/kg. All combinations were used as a bolus mixed in one syringe. Anesthesia induction had been facilitate by propofol administration and then maintained by O<sub>2<sub>/N<sub>2<sub>O/halothane inhalation. Insufficient depth of anesthesia was solved by propofol readministration. As main criteria, the level of sedation, initiative dose of propofol, as well as the need of its readministration had been observed. Furth

Czech name

Klinické zhodnocení kombinace medetomidinu-opioidního agonisty, -parciálního agonisty a agonisty/antagonisty pro premedikaci celkové anestezie u psů

Czech description

Cílem studie bylo zhodnotit klinicky významné účinky kombinace medetomidinu s opioidy - s butorfanolem, buprenorfinem nebo fentanylem. Hodnocenými kritérii byla úroveň sedace po premedikaci, množství propofolu pro indukci a dávka inhalačních anestetik pro vedení anestezie a změna vitálních parametrů v průběhu anestezie. nejlepší sedaci navozovala kombinace s fentanylem, při níž bylo zároveň potřebné i nejmenší množství propofolu pro indukci.

Type

D - Article in proceedings

CEP classification

FP - Other medical fields

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2003

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

8th World Congress of Veterinary Anesthesia

ISBN

5400-5166

ISSN

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e-ISSN

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Number of pages

1

Pages from-to

138

Publisher name

University of Tennessee

Place of publication

Knoxville, Tennessee, USA

Event location

Knoxville, Tennessee, USA

Event date

Sep 16, 2003

Type of event by nationality

WRD - Celosvětová akce

UT code for WoS article

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