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Humoral immune responses during experimental infection with Fascioloides magna and Fasciola hepatica in goats and comparison of their excretory/secretory products

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F07%3A00000603" target="_blank" >RIV/62157124:16170/07:00000603 - isvavai.cz</a>

  • Alternative codes found

    RIV/60077344:_____/07:00096553 RIV/00216208:11310/07:11304 RIV/00027162:_____/07:#0000231 RIV/00216208:11310/07:9P004054

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Humoral immune responses during experimental infection with Fascioloides magna and Fasciola hepatica in goats and comparison of their excretory/secretory products

  • Original language description

    This study investigated the humoral immune responses of goats experimentally infected with Fascioloides magna and Fasciola hepatica to F. magna excretory/secretory products (FmESP) or F. hepatica excretory/secretory products (FhESP), respectively. An enzyme-linked immunosorbent assay (ELISA) was used to determine serum antibody responses and for possible discrimination of F. magna and F. hepatica infections in goats. Comparison of ESPs of both flukes and evaluation of ESP antigenicity was also studied applying immunoblotting techniques. In all infected goats, antibody level was significantly increased (against negative control) since 2 weeks post infection (WPI). However, the dynamics of antibodies varied between F. magna and F. hepatica groups duringthe course of the infection. The cross-reaction of antibodies developed against F. magna and F. hepatica with ESP proteins was recorded by ELISA. The species-specific proteins 40, 120 kDa from FmESP and 80, 160 kDa from FhESP (with no ant

  • Czech name

    Protilátková odpověď během experimentální infekce Fascioloides magna a Fasciola hepatica u koz a srovnání jejich excretory/secretory produktů

  • Czech description

    Tato studie vyšetřuje humorální odpověď imunitního systému u koz experimentálně infikovaných motolicemi F. magna (FmESP) a F. hepatica (FhESP) na ES produkty. Metoda Enzyme-linked immunosorbent assay (ELISA) byla použita k odlišení sérových protilátek odpovědných za rozlišení infekce způsobené F. magna a F. hepatica.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FP - Other medical fields

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2007

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Parasitology Research

  • ISSN

    0932-0113

  • e-ISSN

  • Volume of the periodical

    100

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    5

  • Pages from-to

    549-553

  • UT code for WoS article

  • EID of the result in the Scopus database