Novel biodegradable polydioxanone stents in a rabbit airway model

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F12%3A43870973" target="_blank" >RIV/62157124:16170/12:43870973 - isvavai.cz</a>
Alternative codes found
RIV/60162694:G44__/12:43874167
Result on the web
<a href="http://dx.doi.org/10.1016/j.jtcvs.2011.08.002" target="_blank" >http://dx.doi.org/10.1016/j.jtcvs.2011.08.002</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jtcvs.2011.08.002" target="_blank" >10.1016/j.jtcvs.2011.08.002</a>

Result language
angličtina
Original language name
Novel biodegradable polydioxanone stents in a rabbit airway model
Original language description
This study was undertaken to evaluate safety and biocompatibility of a novel biodegradable polydioxanone stent in a rabbit tracheal model. Metallic and silicone stents represent standard therapeutic approaches for hollow organ stenosis, although complications have been reported repeatedly. Biodegradable stents could reduce the risks associated with this procedure while still achieving the purpose of maintaining lumen patency. METHODS: A commercially available polydioxanone suture strand with a long safety record was used to manufacture the self-expanding stents. The polydioxanone stents were then implanted bronchoscopically and under fluoroscopic guidance into the tracheas of white rabbits (N = 25). Periodic clinical examination was performed. Histopathologic examination concluded the study for the 5 experimental groups at 3, 4, 5, 10, and 15 weeks after implantation.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
GJ - Diseases and animal vermin, veterinary medicine
OECD FORD branch
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Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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