Effect of medetomidine-butorphanol and dexmedetomidine-butorphanol combinations on intraocular pressure in healthy dogs

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F12%3A43871417" target="_blank" >RIV/62157124:16170/12:43871417 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1111/j.1467-2995.2011.00703.x" target="_blank" >http://dx.doi.org/10.1111/j.1467-2995.2011.00703.x</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/j.1467-2995.2011.00703.x" target="_blank" >10.1111/j.1467-2995.2011.00703.x</a>

Result language

angličtina

Original language name

Effect of medetomidine-butorphanol and dexmedetomidine-butorphanol combinations on intraocular pressure in healthy dogs

Original language description

Objective To assess the effects of intravenous (IV) medetomidine-butorphanol and IV dexmedetomidine-butorphanol on intraocular pressure (IOP). Study design Prospective, randomized, blinded clinical study. Animals Forty healthy dogs. Mean +/- SD body mass37.6 +/- 6.6 kg and age 1.9 +/- 1.3 years. Methods Dogs were allocated randomly to receive an IV combination of dexmedetomidine, 0.3 mg m-2, combined with butorphanol, 6 mg m-2, (group DEX) or medetomidine 0.3 mg m-2, combined with butorphanol 6 mg m-2,(group MED). IOP and pulse (PR) and respiratory (fR) rates were measured prior to (baseline) and at 10 (T10), 20 (T20), 30 (T30) and 40 (T40) minutes after drug administration. Oxygen saturation of hemoglobin (SpO2) was monitored following sedation. Data were analyzed by anova followed by Dunnetts tests for multiple comparisons. Changes were considered significant when p { 0.05. Results Following drug administration, PR and fR were decreased significantly at all time points but did not

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Veterinary anaesthesia and analgesia

ISSN

1467-2987

e-ISSN

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Volume of the periodical

39

Issue of the periodical within the volume

3

Country of publishing house

US - UNITED STATES

Number of pages

5

Pages from-to

301-305

UT code for WoS article

000303158700011

EID of the result in the Scopus database

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