Terlipressin in the treatment of late phase catecholamine-resistant septic shock.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F12%3A43871655" target="_blank" >RIV/62157124:16170/12:43871655 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.5754/hge10550" target="_blank" >http://dx.doi.org/10.5754/hge10550</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5754/hge10550" target="_blank" >10.5754/hge10550</a>

Result language

angličtina

Original language name

Terlipressin in the treatment of late phase catecholamine-resistant septic shock.

Original language description

BACKGROUND/AIMS: Norepinephrine, but also dopamine and epinephrine are recommended as first line vasopressors in the treatment of septic shock. In some patients, septic shock deteriorates and becomes to be resistant to catecholamines. In this situation,addition of vasopressin or terlipressin can be advantageous. The aim of our pilot study was to evaluate the impact of terlipressin on open label norepinephrine requirements and mortality. METHODOLOGY: In a randomized, controlled, single centre study we assigned patients with late advanced septic shock refractory to catecholamines (norepinephrine }0.6?g/kg/min for more than 24h) to receive either continuously terlipressin 4mg/24h for 72 hours in addition to open label norepinephrine (TERLI group) or to continue therapy only with catecholamines (CON group). All vasopressor infusions were titrated to maintain a target blood pressure. RESULTS: We enrolled 30 patients, of whom 13 were assigned to terlipressin and in 17 we continued in catech

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

GJ - Diseases and animal vermin, veterinary medicine

OECD FORD branch

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Project

<a href="/en/project/NR9284" target="_blank" >NR9284: Terlipressin in the treatment of catecholamine-resistant septic shock</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Hepato-Gastroenterology

ISSN

0172-6390

e-ISSN

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Volume of the periodical

59

Issue of the periodical within the volume

116

Country of publishing house

GR - GREECE

Number of pages

5

Pages from-to

1043-1047

UT code for WoS article

000305447400021

EID of the result in the Scopus database

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