Distribution of BMP6 in the alveolar bone during mouse mandibular molar eruption.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F14%3A43872934" target="_blank" >RIV/62157124:16170/14:43872934 - isvavai.cz</a>
Alternative codes found
RIV/67985904:_____/14:00437549 RIV/00216224:14310/14:00082217
Result on the web
<a href="http://dx.doi.org/10.3109/03008207.2014.951441" target="_blank" >http://dx.doi.org/10.3109/03008207.2014.951441</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3109/03008207.2014.951441" target="_blank" >10.3109/03008207.2014.951441</a>
Alternative languages
Result language
angličtina
Original language name
Distribution of BMP6 in the alveolar bone during mouse mandibular molar eruption.
Original language description
Eruption requires synchrony of the tooth with the surrounding tissues, particularly the bone. One important step during eruption is emodelling of the alveolar bone at the base of the tooth and along the roots. Expression of BMP6 was reported to be increased in the basal half of the dental follicle prior to eruption and inhibition of BMP6 affected bone formation at the base of the alveolar crypt. The aim of this study was to further investigate BMP6 protein in relation to tooth eruption and the corresponding bone remodelling using temporospatial correlations of BMP6 localization with morphogenetic events (proliferation, differentiation, apoptosis and bone apposition/resorption), other BMPs (BMP2 and BMP7) and three-dimensional images of tooth-bone development. BMP6 expression pattern was mapped in the mandibular molar teeth and related structures around eruption. Localization of BMP6 dominated in osteoblasts, in regions of bone formation within the alveolar crypt. These findings positiv
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
GJ - Diseases and animal vermin, veterinary medicine
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GCP302%2F12%2FJ059" target="_blank" >GCP302/12/J059: Cellular and molecular mechanisms in tooth-bone complex formation</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Connective tissue research
ISSN
0300-8207
e-ISSN
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Volume of the periodical
55
Issue of the periodical within the volume
5-6
Country of publishing house
GB - UNITED KINGDOM
Number of pages
10
Pages from-to
357-366
UT code for WoS article
000344483700006
EID of the result in the Scopus database
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