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Distribution of BMP6 in the alveolar bone during mouse mandibular molar eruption.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F14%3A43872934" target="_blank" >RIV/62157124:16170/14:43872934 - isvavai.cz</a>

  • Alternative codes found

    RIV/67985904:_____/14:00437549 RIV/00216224:14310/14:00082217

  • Result on the web

    <a href="http://dx.doi.org/10.3109/03008207.2014.951441" target="_blank" >http://dx.doi.org/10.3109/03008207.2014.951441</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3109/03008207.2014.951441" target="_blank" >10.3109/03008207.2014.951441</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Distribution of BMP6 in the alveolar bone during mouse mandibular molar eruption.

  • Original language description

    Eruption requires synchrony of the tooth with the surrounding tissues, particularly the bone. One important step during eruption is emodelling of the alveolar bone at the base of the tooth and along the roots. Expression of BMP6 was reported to be increased in the basal half of the dental follicle prior to eruption and inhibition of BMP6 affected bone formation at the base of the alveolar crypt. The aim of this study was to further investigate BMP6 protein in relation to tooth eruption and the corresponding bone remodelling using temporospatial correlations of BMP6 localization with morphogenetic events (proliferation, differentiation, apoptosis and bone apposition/resorption), other BMPs (BMP2 and BMP7) and three-dimensional images of tooth-bone development. BMP6 expression pattern was mapped in the mandibular molar teeth and related structures around eruption. Localization of BMP6 dominated in osteoblasts, in regions of bone formation within the alveolar crypt. These findings positiv

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    GJ - Diseases and animal vermin, veterinary medicine

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GCP302%2F12%2FJ059" target="_blank" >GCP302/12/J059: Cellular and molecular mechanisms in tooth-bone complex formation</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Connective tissue research

  • ISSN

    0300-8207

  • e-ISSN

  • Volume of the periodical

    55

  • Issue of the periodical within the volume

    5-6

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    10

  • Pages from-to

    357-366

  • UT code for WoS article

    000344483700006

  • EID of the result in the Scopus database