Synergistic effects of beta-glucan and resveratrol on platelet aggregation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F14%3A43873320" target="_blank" >RIV/62157124:16170/14:43873320 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Synergistic effects of beta-glucan and resveratrol on platelet aggregation
Original language description
The aim of this study was to verify these data in growing piglets and newly investigate the role of resveratrol during simultaneous ?-glucan supplementation. 6-week-old Large White breed piglets were divided into one control group (C) and two experimental groups: R (resveratrol) and RG (resveratrol + ?-glucan). Resveratrol isolated from Polygonum cuspidatum root and beta-glucan gained from Saccharomyces cerevisiae were soluted in 15% alcohol and administered to the piglets by gastric probe in a daily dose 3 mg/kg0.75 of body weight. Control piglets obtained only alcohol solution. Blood samples were collected by puncture of v. jugularis and tested for number of platelets, platelet aggregation and speed of platelet aggregation after stimulation by ADP and cationic propylgallate. In comparison to control piglets number of platelets dropped markedly in both experimental groups. After one week of supplementation (R: P{0.05; RG: P{0.01) and after 2 weeks (both R and RG: P{0.01). Aggregation
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
GJ - Diseases and animal vermin, veterinary medicine
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů