The effect of deslorelin acetate on the oestrous cycle The effect of deslorelin acetate on the oestrous cycle of female guinea pigs

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F15%3A43873371" target="_blank" >RIV/62157124:16170/15:43873371 - isvavai.cz</a>

Result on the web

<a href="http://www.agriculturejournals.cz/web/vetmed.htm?volume=60&firstPage=155&type=publishedArticle" target="_blank" >http://www.agriculturejournals.cz/web/vetmed.htm?volume=60&firstPage=155&type=publishedArticle</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.17221/8062-VETMED" target="_blank" >10.17221/8062-VETMED</a>

Result language

angličtina

Original language name

The effect of deslorelin acetate on the oestrous cycle The effect of deslorelin acetate on the oestrous cycle of female guinea pigs

Original language description

Deslorelin acetate, a GnRH agonist, is commonly used to prevent folliculogenesis in several species. However, little is known of the effect of deslorelin acetate implants on the oestrous cycle of female guinea pigs. Fifteen intact healthy female guinea pigs were investigated in this study. Signs of sexual behaviour, the presence of a vaginal membrane along with plasma concentrations of oestradiol (E2) and progesterone (P4), were monitored during two consecutive oestrous cycles. At the beginning of the third oestrous cycle each guinea pig was administered an implant of the GnRH analogue, deslorelin acetate, (4.7 mg). When compared to the untreated state, deslorelin implantation was associated with altered signs of oestrus. The average time to opening ofthe vaginal membrane was delayed. After opening, the vaginas were found to be variably opened and closed. A significant reduction in P4 (to less than 1.0 ng/ml) and cessation of P4 cyclical variation was observed. Plasma E2 remained high

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

GJ - Diseases and animal vermin, veterinary medicine

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Veterinární medicína

ISSN

0375-8427

e-ISSN

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Volume of the periodical

60

Issue of the periodical within the volume

3

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

6

Pages from-to

155-160

UT code for WoS article

000352558900005

EID of the result in the Scopus database

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