The effects of salicylic acid on juvenile zebrafish Danio rerio under flow-through conditions
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F16%3A43874359" target="_blank" >RIV/62157124:16170/16:43874359 - isvavai.cz</a>
Alternative codes found
RIV/62157124:16270/16:43874359
Result on the web
<a href="http://dx.doi.org/10.1007/s00128-016-1877-5" target="_blank" >http://dx.doi.org/10.1007/s00128-016-1877-5</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00128-016-1877-5" target="_blank" >10.1007/s00128-016-1877-5</a>
Alternative languages
Result language
angličtina
Original language name
The effects of salicylic acid on juvenile zebrafish Danio rerio under flow-through conditions
Original language description
The aquatic environment is becoming increasingly contaminated with pharmaceuticals. Salicylic acid (SA), which can be used individually or appear as a degradation product of the widely used acetylsalicylic acid was chosen for testing. Juvenile zebrafish Danio rerio were subjected to OECD test No. 215 (fish, juvenile growth test) with salicylic acid concentrations of 0.004; 0.04; 0.4; 4 and 40 mg/L. Specific growth rate (SGR), histological changes, and parameters of oxidative stress were evaluated. SA had no effects on histological changes, SGR, glutathione reductase, and lipid peroxidation. Increased catalytic activity of glutathione peroxidase was found at 0.04 mg/L compared to control, increased catalytic activity of catalase was found at 0.04 and 4 mg/L compared to control, and increased catalytic activity of glutathione-S-transferase was found at 0.004 and 0.04 mg/L compared to control (P<0.05). Juvenile zebrafish turned out to be relatively insensitive to both environmentally relevant (0.004 mg/L) and higher concentrations of salicylic acid.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
GJ - Diseases and animal vermin, veterinary medicine
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Bulletin of environmental contamination and toxicology
ISSN
0007-4861
e-ISSN
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Volume of the periodical
97
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
323-330
UT code for WoS article
000382149000005
EID of the result in the Scopus database
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