Intravenous alfaxalone anaesthesia in leopard geckos (Eublepharis macularius).

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F18%3A43876937" target="_blank" >RIV/62157124:16170/18:43876937 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1053/j.jepm.2017.08.008" target="_blank" >http://dx.doi.org/10.1053/j.jepm.2017.08.008</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1053/j.jepm.2017.08.008" target="_blank" >10.1053/j.jepm.2017.08.008</a>

Result language

angličtina

Original language name

Intravenous alfaxalone anaesthesia in leopard geckos (Eublepharis macularius).

Original language description

Intravenous alfaxalone, administered at a dose of 5mg/kg in the jugular vein, was evaluated in 20 leopard geckos (Eublepharis macularius) to ascertain its ability to provide a level of anaesthesia. The induction time, time to loss of mandibular tone, interval of deep anaesthesia, and full recovery time were27.5 ? 30.7 seconds(10 to 56seconds),1.3 ? 1.4 minutes (11seconds to 4minutes),12.5 ? 2.2 minutes(11.11 to 15.39 minutes), and18.8 ? 12.1 minutes (10.4 to 52.31minutes), respectively. A significant reduction in heart rate (74 ? 12.9 beats/minute) between 2 and 24 minutes after alfaxalone administration was recorded. A significant decrease of respiratory rate (26.8 ? 10.1 breaths/minute) was recorded 2 minutes after alfaxalone administration and respiratory rate remained lower than basal respiratory (31.4 ? 3.1 breaths/minute) for 24minutes,but without statistical significance. The intravenous administration of alfaxalone in leopard geckos achieved a rapid onset of anasthesia and a suitable recovery time. Based on this investigation the afaxalone dose and administration site has proved to be a suitable protocol for sedation before tracheal intubation through maintenance on gas anaesthesia. Moreover, the administration technique, jugular administration of the drug, was acceptable in leopard geckos, in which other venipuncture sites are challenging or inaccessible.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

40301 - Veterinary science

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Exotic Pet Medicine

ISSN

1557-5063

e-ISSN

—

Volume of the periodical

27

Issue of the periodical within the volume

3

Country of publishing house

US - UNITED STATES

Number of pages

4

Pages from-to

11-14

UT code for WoS article

000440126200003

EID of the result in the Scopus database

2-s2.0-85047609953