All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Novel functions of caspase-9 in endochondral bone development

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F19%3A43877597" target="_blank" >RIV/62157124:16170/19:43877597 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Novel functions of caspase-9 in endochondral bone development

  • Original language description

    Caspase-9, as an initiator of the mitochondrial apoptotic pathway, triggers cell death by activation of the effector caspases -3, -6 and -7. Currently, the action of caspases has been re-evaluated because of their nonapoptotic roles in many systems. We have previously shown non-apoptotic activation of pro-apoptotic caspases during bone development. Here we have focused on caspase-9, which becomes activated in nonapoptotic chondrocytes of the growth plate of endochondral (long) bones.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    10608 - Biochemistry and molecular biology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů