Investigation of pathological haemorrhage in Maine Coon cats

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F20%3A43878474" target="_blank" >RIV/62157124:16170/20:43878474 - isvavai.cz</a>

Result on the web

<a href="https://bvajournals.onlinelibrary.wiley.com/journal/20427670" target="_blank" >https://bvajournals.onlinelibrary.wiley.com/journal/20427670</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1136/vr.105503" target="_blank" >10.1136/vr.105503</a>

Result language

angličtina

Original language name

Investigation of pathological haemorrhage in Maine Coon cats

Original language description

Objective Afibrinogenaemic haemorrhage was previously reported in a Maine Coon cat. Two littermates subsequently died from surgical non-haemostasis, suggesting a hereditable coagulopathy. Methods We prospectively recruited cats which were: a) Maine Coons with pathological haemorrhage (group 1, n=8), b) healthy familial relatives of group 1 (group 2, n=13) and c) healthy Maine Coons unrelated to groups 1 and 2 (group 3, n=12). Coagulation tests: prothrombin time, activated partial thromboplastin time and thrombin clotting time (TCT) were performed on citrated plasma along with quantification of fibrinogen. Routine haematological examination was performed on EDTA-anticoagulated blood collected contemporaneously. Results Thirty-three blood samples were analysed. Fibrinogen concentrations were significantly reduced in groups 1 (P&lt;0.01) and 2 (P&lt;0.01) compared with group 3. Similarly, TCT was found to be significantly extended in group 1 (P&lt;0.01) and group 2 (P=0.02) with respect to group 3. Conclusions Dysfibrinogenaemia was identified in clinical cases and their healthy relatives, suggesting that this may represent a hereditary condition of Maine Coon cats. Clinicians should be aware of the increased potential for non-haemostasis in this cat breed and consider assessing clotting function before (elective) surgery.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

40301 - Veterinary science

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Veterinary Record

ISSN

0042-4900

e-ISSN

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Volume of the periodical

187

Issue of the periodical within the volume

9

Country of publishing house

GB - UNITED KINGDOM

Number of pages

17

Pages from-to

1-16

UT code for WoS article

000608475200012

EID of the result in the Scopus database

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