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Nephromegaly due to Disruption of Nephrons in the Green Iguana (Iguana iguana)

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F20%3A43878701" target="_blank" >RIV/62157124:16170/20:43878701 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.sciencedirect.com/science/article/pii/S0021997520301171?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0021997520301171?via%3Dihub</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.jcpa.2020.09.008" target="_blank" >10.1016/j.jcpa.2020.09.008</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Nephromegaly due to Disruption of Nephrons in the Green Iguana (Iguana iguana)

  • Original language description

    We describe a fatal kidney disease in green iguanas (Iguana iguana), associated with severe nephromegaly. Affected animals have enlarged kidneys, which fill the pelvic cavity, leading to compression of adjacent organs, obstipation and, ultimately, death. The pathological features of this disease have been poorly described and its aetiology is unknown. We performed detailed gross and histological analyses of 17 green iguanas with a clinical diagnosis of nephromegaly, and compared the results with those of eight healthy controls. Grossly, the kidneys of all 17 individuals were markedly enlarged and the distal colons were distended and overfilled with faecal contents. Histopathological examination revealed that these enlarged kidneys consisted mainly of tubular hyperplasia, resembling poorly developed proximal segments. The nephrogenic zones were either poorly developed or absent. There was a reduction in the density of glomeruli and the distal segments were reduced in number. There was no histological evidence of an aetiology for the nephron disruption and nephromegaly.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    40301 - Veterinary science

Result continuities

  • Project

  • Continuities

    N - Vyzkumna aktivita podporovana z neverejnych zdroju

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of comparative pathology

  • ISSN

    0021-9975

  • e-ISSN

  • Volume of the periodical

    181

  • Issue of the periodical within the volume

    NOV

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    6

  • Pages from-to

    1-6

  • UT code for WoS article

    000597961600001

  • EID of the result in the Scopus database

    2-s2.0-85093688399