Repeated bouts of pulmonary tuberculosis in a hunting cat: reinfection or recrudescence?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F21%3A43879264" target="_blank" >RIV/62157124:16170/21:43879264 - isvavai.cz</a>

Result on the web

<a href="https://journals.sagepub.com/doi/10.1177/2055116921990292" target="_blank" >https://journals.sagepub.com/doi/10.1177/2055116921990292</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1177/2055116921990292" target="_blank" >10.1177/2055116921990292</a>

Result language

angličtina

Original language name

Repeated bouts of pulmonary tuberculosis in a hunting cat: reinfection or recrudescence?

Original language description

Case summary A 7-year-old neutered male Siamese cat was referred for investigation of weight loss and hypercalcaemia (3.3 mmol/l; reference interval 2?3 mmol/l). Haematology, serum biochemistry, thoracic imaging, bronchoalveolar lavage (BAL), Ziehl?Neelsen staining of the BAL fluid and interferon gamma release assay (IGRA) were compatible with pneumonia caused by the less pathogenic member of the Mycobacterium tuberculosis complex, that is, M microti (the ?vole bacillus?), which is common in cats in the UK. Treatment with azithromycin, rifampicin and marbofloxacin was given for 2 months, followed by 4 months of azithromycin and marbofloxacin. Treatment recommendations for tuberculous pneumonia have since changed. The cat remained asymptomatic for 1 year but went on to develop M microti pneumonia on five other occasions, and was treated for 6?12 months on each occasion. The patient?s clinical signs, hypercalcaemia and radiographic/CT pulmonary pathology always resolved completely, and the IGRA became negative, before antimycobacterial treatment was stopped. This suggests cure followed by reinfection owing to avid hunting behaviour. Alternatively, this could represent recrudescence of dormant disease. This case has previously been included in a study that described a series of cases of feline tuberculosis. Relevance and novel information This case shows that M microti infection in cats can present as recurrent episodes of pneumonia, even after prolonged treatment courses.

Czech name

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Czech description

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Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

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OECD FORD branch

40301 - Veterinary science

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Feline Medicine and Surgery Open Reports

ISSN

2055-1169

e-ISSN

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Volume of the periodical

7

Issue of the periodical within the volume

7

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

1-6

UT code for WoS article

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EID of the result in the Scopus database

2-s2.0-85104249966