Detection of Helicobacter-like organisms in dogs with chronic gastric and intestinal inflammation.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F24%3A43881175" target="_blank" >RIV/62157124:16170/24:43881175 - isvavai.cz</a>

Alternative codes found

RIV/62157124:16270/24:43881175

Result on the web

<a href="https://doi.org/10.2754/avb202493010037" target="_blank" >https://doi.org/10.2754/avb202493010037</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2754/avb202493010037" target="_blank" >10.2754/avb202493010037</a>

Result language

angličtina

Original language name

Detection of Helicobacter-like organisms in dogs with chronic gastric and intestinal inflammation.

Original language description

Abstract: In humans, Helicobacter pylori and some other members of Helicobacteraceae are known to be implicated in both inflammatory and non-inflammatory gastrointestinal disorders. So far, conclusive evidence regarding the potential involvement of helicobacters in development of chronic inflammatory lesions of canine stomach and intestine is missing. The aim of the study was to determine the prevalence of Helicobacter-like organisms in endoscopic biopsy samples of different parts of the gastrointestinal tract of dogs with chronic inflammation and to reveal their potential relationship to the presence and severity of morphological and inflammatory changes. A total of 183 samples of inflammatory lesions were examined histologically and immunohistochemically. Helicobacter-like organisms were found in 64.1% of samples of gastritis, 5.3% of cases of duodenitis, 47.6% of cases of ileitis and 48% of cases of colitis. The most frequent gastric morphological change was surface epithelial injury. In duodenum epithelial injury together with villous stunting, and in ileum villous stunting were the most commonly observed morphological changes. Crypt dilation/ distortion was the most frequent morphological abnormality among colonic samples and was significantly more often a feature of colitis than duodenitis and ileitis. Our data show no effect of colonization with Helicobacter-like organisms on the presence of gastric pit epithelial injury and gastric mucosal fibrosis. No association was found between the presence/density of Helicobacter-like organisms and the presence or severity of morphological and inflammatory lesions of duodenal, ileal, and colonic mucosa.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

40301 - Veterinary science

Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta veterinaria Brno

ISSN

0001-7213

e-ISSN

1801-7576

Volume of the periodical

93

Issue of the periodical within the volume

1

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

7

Pages from-to

37-43

UT code for WoS article

001199853700006

EID of the result in the Scopus database

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