Comparison of Campylobacter coli isolated from pigs and humans in the Czech Republic

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F11%3A43870464" target="_blank" >RIV/62157124:16270/11:43870464 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Comparison of Campylobacter coli isolated from pigs and humans in the Czech Republic
Original language description
The aim of this study is to compare pulsed field gel electrophoresis (PFGE - SmaI) subtypes and antimicrobial resistance of Campylobacter coli isolated from human patients and slaughtered pigs. The MIC values and presence of genes associated with resistance to ampicillin, ciprophloxacine, nalidixic acid, erythromycine, gentamycine, chloramphenicol and tetracycline for C. coli from humans (55) and pigs (188) were compared. Isolates from pigs were maily resistant to erythromycine (63%) with mutation A2075G in 23S rRNA gene also detected and tetracycline (48%) with tetO gene presence detected. Resistance to fluoroquinolones was low (27%). On the other hand isolates from human patients were highly resistant to nalidixic acid (49%), ciprofloxacine (46%) with Thr86Ile mutation in gyrA gene detected; erythromycin (24%) and tetracycline (6%). PFGE patterns were grouped into clusters of at least 80% genetic similarity. Among 55 human isolates 80% had unique genotypes; 20% represented five clust
Czech name
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Czech description
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Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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