Effects of mixture of pharmaceuticals on early life stages of tench (Tinca tinca)
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F14%3A43872886" target="_blank" >RIV/62157124:16270/14:43872886 - isvavai.cz</a>
Alternative codes found
RIV/68081766:_____/14:00427896 RIV/62157124:16170/14:43872886
Result on the web
<a href="http://dx.doi.org/10.1155/2014/253468" target="_blank" >http://dx.doi.org/10.1155/2014/253468</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2014/253468" target="_blank" >10.1155/2014/253468</a>
Alternative languages
Result language
angličtina
Original language name
Effects of mixture of pharmaceuticals on early life stages of tench (Tinca tinca)
Original language description
Ubiquitous occurrence of pharmaceuticals in aquatic environment results in concern about potential adverse the effects on nontarget organisms. In water, drugs are present in complex mixtures, in which complicated interactions affect toxicity of single components. The purpose of this study was to examine effect of 35-day-long exposure to mixture of ibuprofen, diclofenac, and carbamazepine on the mortality, growth, early ontogeny, and histopathological changes in tench (Tinca tinca). Early life stage toxicity test was carried out using a modified protocol according to OECD guideline 210. Exposure to mixture of pharmaceuticals at concentration of 60 mu g.L-1 for each substance was associated with significant increase in mortality, as well as significant increase in growth and elevated incidence of malformations. Any of the tested concentrations resulted in histopathological changes of liver, kidney, skin, or gill. After fourteen days of exposure there was short-termdelay of development re
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
GJ - Diseases and animal vermin, veterinary medicine
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biomed Research International
ISSN
2314-6133
e-ISSN
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Volume of the periodical
2014
Issue of the periodical within the volume
2014
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
253468
UT code for WoS article
000333627400001
EID of the result in the Scopus database
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