Oxidative stress and liver damage in birds exposed to diclofenac and lead

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F14%3A43872898" target="_blank" >RIV/62157124:16270/14:43872898 - isvavai.cz</a>

Alternative codes found

RIV/60162694:G44__/14:43875309 RIV/62157124:16170/14:43872898

Result on the web

<a href="http://dx.doi.org/10.2754/avb201483040299" target="_blank" >http://dx.doi.org/10.2754/avb201483040299</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2754/avb201483040299" target="_blank" >10.2754/avb201483040299</a>

Result language

angličtina

Original language name

Oxidative stress and liver damage in birds exposed to diclofenac and lead

Original language description

Responses of wildlife to multiple stressors fit in the ecological concept of trade-off. While toxicity of non-steroidal anti-inflammatory drugs and heavy metals for free-ranging birds has been shown in single exposures, the present study aims to evaluateoxidative stress, and liver and kidney damage caused by single and combined effects of diclofenac and lead in the Japanese quail. Forty Japanese quail (Coturnix coturnix japonica) were divided into equal groups of controls, diclofenac, Pb, and Pb+diclofenac exposures. The birds were exposed to the respective chemicals through insertion of lead shots (1.5 g) into the crop on day 0 of the experiment and/ or administration of 5 mg/kg of diclofenac intramuscularly in two treatments on days 0 and 5. Groupsin liver and kidney tissues of birds were then compared after 10 days using histopathology and biochemistry markers such as glutathione reductase (GR), ferric reducing antioxidant power (FRAP), and lipid peroxidation measured as total thi

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

GJ - Diseases and animal vermin, veterinary medicine

OECD FORD branch

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Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta veterinaria Brno

ISSN

0001-7213

e-ISSN

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Volume of the periodical

83

Issue of the periodical within the volume

4

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

6

Pages from-to

299-304

UT code for WoS article

000346604900004

EID of the result in the Scopus database

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