The effect of antidepressants in surface water on Danio rerio organism

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F18%3A43876970" target="_blank" >RIV/62157124:16270/18:43876970 - isvavai.cz</a>
Alternative codes found
RIV/00027162:_____/19:N0000156
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
The effect of antidepressants in surface water on Danio rerio organism
Original language description
The concentration of antidepressants occurring in surface water is rising worldwide because of their ineffective removal at wastewater treatment plants. However, the knowledge of their impact on aquatic organisms is limited. For our assay, three different antidepressants with different mechanisms of action were chosen to assess the impact on the Danio rerio body formation mechanism. The antidepressants were tested in two concentrations ? environmentally-relevant (according to literature sources) and 100x higher. The method used was relative gene expression and genes were selected as representatives of the heart, brain, spine, eye and mesoderm formation. The results showed that the gene expression mechanism and welfare status are disrupted already in environmentally-relevant concentrations.
Czech name
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Czech description
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Project
<a href="/en/project/LO1218" target="_blank" >LO1218: Healthy animal as a source of wholesome food</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
MendelNet 2018 - Proceedings of 25th International PhD Students Conference
ISBN
978-80-7509-597-8
ISSN
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e-ISSN
neuvedeno
Number of pages
5
Pages from-to
160-164
Publisher name
Mendelova univerzita v Brně
Place of publication
Brno
Event location
Brno
Event date
Nov 7, 2018
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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