Effects of waterborne antidepressants on non-target animals living in the aquatic environment: A review

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F18%3A43877014" target="_blank" >RIV/62157124:16270/18:43877014 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1016/j.scitotenv.2018.03.076" target="_blank" >http://dx.doi.org/10.1016/j.scitotenv.2018.03.076</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.scitotenv.2018.03.076" target="_blank" >10.1016/j.scitotenv.2018.03.076</a>

Result language

angličtina

Original language name

Effects of waterborne antidepressants on non-target animals living in the aquatic environment: A review

Original language description

After application, antidepressants, like other pharmaceuticals, are excreted from human body in their native form or as metabolites and enter the aquatic environment via different pathways. As concentrations of antidepressant residues in water continue to increase, their effects on non-target animals are being discussed. The aim of this study is to summarize current knowledge about the effects of wateborne antidepressants on non-target animals living in surface waters - invertebrates, fish and amphibians. Selective serotonin reuptake inhibitors such as fluoxetine, sertraline, and citalopram have been found to effect behavior, reproduction, and development in both invertebrates and vertebrates. Venlafaxine, belonging to the group of selective serotonin-noradrenalin reuptake inhibitors, not only affected behavior but also showed the potential to reduce survival in fish. Tricylic antidepressants are known to have various side-effectswhen consumed by humans. Moreover, in fish, exposure resulted in a significant increase in mortality, developmental retardation, morphological anomalies, and pathological changes in brain, heart, and cranial and caudal kidney. In addition, changes in antioxidant enzyme activity as well as increased lipid peroxidation were observed, even at the lowest tested concentrations. According to current knowledge, antidepressants occuring in surface water are able to affect the behavior, reproduction, development, and survival of aquatic invertebrates and vertebrates. (C) 2018 Elsevier B.V. All rights reserved.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

40301 - Veterinary science

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Science of the Total Environment

ISSN

0048-9697

e-ISSN

—

Volume of the periodical

631-632

Issue of the periodical within the volume

August

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

6

Pages from-to

789-794

UT code for WoS article

000432471900080

EID of the result in the Scopus database

2-s2.0-85043535722