IncI1 ESBL-producing plasmids from Escherichia coli obtained from patients are closely related to plasmids from E. coli of animal origin
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F19%3A43878238" target="_blank" >RIV/62157124:16270/19:43878238 - isvavai.cz</a>
Alternative codes found
RIV/62157124:16810/19:43878238
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
IncI1 ESBL-producing plasmids from Escherichia coli obtained from patients are closely related to plasmids from E. coli of animal origin
Original language description
Twelve E. coli isolates sharing identical ESBL genes and pMLST were sequenced on Illumina and MinION platforms. The IncI1/ST3 plasmids were obtained from ten E. coli isolates (two from patients with bloodstream infections, six from food and two from animals). The IncI1/ST7 plasmids originated from E. coli isolates from a patient with bloodstream infection and from a pig. Sequences of IncI1/ST3 and IncI1/ST7 plasmids harbouring blaCTX-M-1 retrieved from GenBank were used for comparison within the respective group. The ten IncI1/ST3 and two IncI1/ST7 plasmids carrying blaCTX-M-1 were highly similar in structure and organization with only minor rearrangements and differences in the variable region. The high level of similarity was also observed in plasmids from E. coli of animal origin from Australia, Switzerland, the Netherlands and France. This study revealed high level of similarity in organization, structure and accessory regions of IncI1/ST3 and IncI1/ST7 plasmids, respectively. These findings suggest broad dissemination of a very successful blaCTX-M-1- carrying plasmid lineages among E. coli of both human and animal origin.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
10606 - Microbiology
Result continuities
Project
<a href="/en/project/NV18-09-00605" target="_blank" >NV18-09-00605: Enterobacteriaceae resistant to carbapenems and colistin: One-Health approach in addressing human and non-human sources of emerging antimicrobial resistance mechanisms</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů