Evaluation of the glutathione concentration in whole blood of dairy Holstein cows

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F21%3A43879719" target="_blank" >RIV/62157124:16270/21:43879719 - isvavai.cz</a>

Result on the web

<a href="https://www.agriculturejournals.cz/web/vetmed.htm?type=article&id=157_2020-VETMED" target="_blank" >https://www.agriculturejournals.cz/web/vetmed.htm?type=article&id=157_2020-VETMED</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.17221/157/2020-VETMED" target="_blank" >10.17221/157/2020-VETMED</a>

Result language

angličtina

Original language name

Evaluation of the glutathione concentration in whole blood of dairy Holstein cows

Original language description

The objective of this study was to evaluate the concentrations of the total ( T-GSH), oxidised (GSSG) and reduced (GSH) glutathione in the blood of dairy cows, assess the relationships of the phase and number of lactation, milk production, body condition score (BCS) and selected biochemical parameters on its concentrations. We analysed 79 samples of whole blood from dairy Holstein cows. The concentration of glutathione was assessed by the spectrophotometric enzymatic method. The whole dataset shows the mean concentration of T-GSH, GSSG and GSH of 803 +/- 22 mu mol/l, 23 +/- 2.5 mu mol/l and 757 +/- 27 mu mol/l, respectively. The GSH/GSSG ratio was 95 +/- 17. The phase of the lactation had a significant impact on the levels of T-GSH and GSH, but the number of lactation and BCS had no effect. Dry cows had higher levels of T-GSH ( 938 +/- 44 mu mol/l) than the fresh (713 +/- 46 mu mol/l) and peak lactation (785 +/- 45 mu mol/l) cows. The fresh cows had significantly lower concentrations of GSH (618 +/- 44 mu mol/l) than the peak lactation ( 719 +/- 46 mu mol/l) and dry cows ( 827 +/- 43 mu mol/l). On the basis of a regression analysis, blood glutathione was affected mainly by the liver function and energy metabolism. Glutathione as the marker of oxidation stress seems to be a promising tool in monitoring the health and welfare of the herd, yet intensive research in this field remains necessary.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

40301 - Veterinary science

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Veterinární medicína

ISSN

0375-8427

e-ISSN

—

Volume of the periodical

66

Issue of the periodical within the volume

5

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

10

Pages from-to

179-188

UT code for WoS article

000647289900001

EID of the result in the Scopus database

2-s2.0-85107475060