The effect of sulfamethoxazole on oxidative stress indices in zebrafish (Danio rerio)
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F21%3A43879748" target="_blank" >RIV/62157124:16270/21:43879748 - isvavai.cz</a>
Result on the web
<a href="https://www.tandfonline.com/doi/full/10.1080/01480545.2018.1560465" target="_blank" >https://www.tandfonline.com/doi/full/10.1080/01480545.2018.1560465</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/01480545.2018.1560465" target="_blank" >10.1080/01480545.2018.1560465</a>
Alternative languages
Result language
angličtina
Original language name
The effect of sulfamethoxazole on oxidative stress indices in zebrafish (Danio rerio)
Original language description
The aim of this study was to assess the impact of sulfamethoxazole (SMX) on oxidative stress indices in zebrafish (Danio rerio). The test was completed after 14 days. The tested concentrations were 50, 100 and 500 mu g/L of SMX. Glutathione peroxidase, glutathione reductase, glutathione S-transferase and lipid peroxidation were investigated to determine the effects of SMX on oxidative stress in zebrafish. Lipid peroxidation gradually increased slightly (but non-significantly) at all tested concentrations during the test as compared to the control. The evaluation of oxidative stress biomarkers showed no significant changes in the activity of antioxidant enzymes in any experimental group exposed to SMX as compared to the control. The gradual increase in lipid peroxidation after 3 and 14 days in the SMX treated groups as compared to the control group indicates increasing cell membrane damage.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
40301 - Veterinary science
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Drug and chemical toxicology
ISSN
0148-0545
e-ISSN
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Volume of the periodical
44
Issue of the periodical within the volume
1
Country of publishing house
GB - UNITED KINGDOM
Number of pages
6
Pages from-to
58-63
UT code for WoS article
000596184100001
EID of the result in the Scopus database
2-s2.0-85097183443