Genomic Analysis of an I1 Plasmid Hosting a sul3-Class 1 Integron and bla(SHV-12) within an Unusual Escherichia coli ST297 from Urban Wildlife
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F22%3A43880037" target="_blank" >RIV/62157124:16270/22:43880037 - isvavai.cz</a>
Alternative codes found
RIV/62157124:16810/22:43880037 RIV/65269705:_____/22:00077569
Result on the web
<a href="https://www.mdpi.com/2076-2607/10/7/1387" target="_blank" >https://www.mdpi.com/2076-2607/10/7/1387</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/microorganisms10071387" target="_blank" >10.3390/microorganisms10071387</a>
Alternative languages
Result language
angličtina
Original language name
Genomic Analysis of an I1 Plasmid Hosting a sul3-Class 1 Integron and bla(SHV-12) within an Unusual Escherichia coli ST297 from Urban Wildlife
Original language description
Wild birds, particularly silver gulls (Chroicocephalus novaehollandiae) that nest near anthropogenic sites, often harbour bacteria resistant to multiple antibiotics, including those considered of clinical importance. Here, we describe the whole genome sequence of Escherichia coli isolate CE1867 from a silver gull chick sampled in 2012 that hosted an I1 pST25 plasmid with bla(SHV-12), a beta-lactamase gene that encodes the ability to hydrolyze oxyimino beta-lactams, and other antibiotic resistance genes. Isolate CE1867 is an ST297 isolate, a phylogroup B1 lineage, and clustered with a large ST297 O130:H11 Glade, which carry Shiga toxin genes. The I1 plasmid belongs to plasmid sequence type 25 and is notable for its carriage of an atypical sul3-class 1 integron with mefB(Delta 260), a structure most frequently reported in Australia from swine. This integron is a typical example of a Tn21-derived element that captured sul3 in place of the standard sull structure. Interestingly, the mercury resistance (mer) module of Tn21 is missing and has been replaced with Tn2-bla(TEM-1) and a bla(SHV-12) encoding module flanked by direct copies of IS26. Comparisons to similar plasmids, however, demonstrate a closely related family of ARG-carrying plasmids that all host variants of the sul3-associated integron with conserved Tn21 insertion points and a variable presence of both mer and mefB truncations, but predominantly mefB(Delta 260).
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10606 - Microbiology
Result continuities
Project
<a href="/en/project/GA18-23532S" target="_blank" >GA18-23532S: Multiresistant high-risk Escherichia coli lineages: a success story of the chromosome and plasmid interplays</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Microorganisms
ISSN
2076-2607
e-ISSN
2076-2607
Volume of the periodical
10
Issue of the periodical within the volume
7
Country of publishing house
CH - SWITZERLAND
Number of pages
13
Pages from-to
nestrankovano
UT code for WoS article
000833411700001
EID of the result in the Scopus database
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