Pesticides and parabens contaminating aqutic environment: acute and sub-chronic toxicity towards early-life stages of freshwater fish and amphibians

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F23%3A43880705" target="_blank" >RIV/62157124:16270/23:43880705 - isvavai.cz</a>

Alternative codes found

RIV/62157124:16170/23:43880705

Result on the web

<a href="https://doi.org/10.3390/toxics11040333" target="_blank" >https://doi.org/10.3390/toxics11040333</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/toxics11040333" target="_blank" >10.3390/toxics11040333</a>

Result language

angličtina

Original language name

Pesticides and parabens contaminating aqutic environment: acute and sub-chronic toxicity towards early-life stages of freshwater fish and amphibians

Original language description

Pesticides and personal care products are two very important groups of contaminants posing a threat to the aquatic environment and the organisms living in it.. Therefore, this study aimed to describe the effects of widely used pesticides and parabens on aquatic non-target biota such as fish (using model organisms Danio rerio and Cyprinus carpio) and amphibians (using model organism Xenopus laevis) using a wide range of endpoints. The first part of the experiment was focused on the embryonal toxicity of three widely used pesticides (metazachlor, prochloraz, and 4-chloro-2-methyl phenoxy acetic acid) and three parabens (methylparaben, propylparaben, and butylparaben) with D. rerio, C. carpio, and X. laevis embryos. An emphasis was placed on using mostly sub-lethal concentrations that are partially relevant to the environmental concentrations of the substances studied. In the second part of the study, an embryo-larval toxicity test with C. carpio was carried out with prochloraz using concentrations 0.1, 1, 10, 100, and 1000 µg/L. The results of both parts of the study show that even the low, environmentally relevant concentrations of the chemicals tested are often able to affect the expression of genes that play either a prominent role in detoxification and sex hormone production or indicate cell stress or, in case of prochloraz, to induce genotoxicity.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30105 - Physiology (including cytology)

Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Toxics

ISSN

2305-6304

e-ISSN

2305-6304

Volume of the periodical

11

Issue of the periodical within the volume

4

Country of publishing house

CH - SWITZERLAND

Number of pages

23

Pages from-to

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UT code for WoS article

000979550600001

EID of the result in the Scopus database

2-s2.0-85153729422