The use of tripeptide conformation families in protein model building

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F06%3A00000737" target="_blank" >RIV/62157124:16370/06:00000737 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

The use of tripeptide conformation families in protein model building

Original language description

Conformation family is a useful concept for classification of proteins and nucleic acid structures. This classification is used in methods for prediction of protein structures, various model building programs, and as a tool for protein structure verification. There is no clear definition of conformation family in the literature. Clusters of similar structures usually represent conformation family. Conformation families for tripeptides were determined by a method of conformation-family search in multidimensional torsion-angle space [1]. The families were classified according to positions in the Ramachandran map and studied for the purpose of automatic protein model building. The model building method was tested on a green fluorescent protein which is frequently used as a reporter protein [2]. The crystal structure with PDB code 1EMB was selected for the testing. The structure of the protein was build up automatically with a program NUT [3] and the structure building was analyzed in deta

Czech name

Využití konformačních rodin tripeptidů pro tvorbu modelů peptidů

Czech description

Konformační modely rodin tripeptidů, zjištěné metodou hledání konformačních rodin v mnoharozměrném prostoru torzních úhlů, byly klasifikovány dle svých pozic v Ramachandranově mapě a studovány pro účely automatického modelování proteinů, jež bylo následně provedeno na zeleném fluoreskujícím priteinu. Výsledky byly porovnány s modely vytvořenými na základě mono- a dipeptidů.

Type

M - Conference organization

CEP classification

CE - Biochemistry

OECD FORD branch

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Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2006

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Event location

Piešťany

Event country

SK - SLOVAKIA

Event starting date

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Event ending date

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Total number of attendees

200

Foreign attendee count

180

Type of event by attendee nationality

EUR - Evropská akce