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Ring-substituted 4-Hydroxy-1H-quinolin-2-ones: Preparation and Their Photosynthesis-inhibiting Activity

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F08%3A00002046" target="_blank" >RIV/62157124:16370/08:00002046 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Ring-substituted 4-Hydroxy-1H-quinolin-2-ones: Preparation and Their Photosynthesis-inhibiting Activity

  • Original language description

    The series of twelve ring-substituted 4-hydroxy-1H-quinolin-2-one derivatives were prepared. The synthetic procedures of the compounds are presented. All the prepared quinoline derivatives were analyzed using RP-HPLC method for the lipophilicity measurement and their lipophilicity was determined. The prepared compounds were tested for their photosynthesis-inhibiting activity (the inhibition of photosynthetic electron transport in spinach chloroplasts (Spinacia oleracea L.). The relationships between thelipophilicity and the chemical structure of the studied compounds are discussed as well as the structure-activity relationships (SAR) between the chemical structure and the biological activities of the evaluated compounds.

  • Czech name

    Na jádře substituované 4-hydroxy-1H-chinolin-2-ony: příprava a jejich inhibiční účinek na fotosyntézu

  • Czech description

    Série 12 substituovaných hydroxy-1H-chinolin-2-onů byla připravena a otestována na schopnost inhibovat fotosyntézu. Z výsledků byly odvozeny vztahy mezi strukturou a aktivitou.

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    FR - Pharmacology and apothecary chemistry

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    proceedings of 12th International Electronic Conference on Synthetic Organic Chemistry

  • ISBN

    3-906980-20-0

  • ISSN

  • e-ISSN

  • Number of pages

    1

  • Pages from-to

  • Publisher name

    Molecular Diversity Preservation International (MDPI)

  • Place of publication

    Basel

  • Event location

  • Event date

  • Type of event by nationality

  • UT code for WoS article