Recent Advances in Design of Potential Quinoxaline Anti-Infectives

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F14%3A43872712" target="_blank" >RIV/62157124:16370/14:43872712 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.2174/0929867321666141011194825" target="_blank" >http://dx.doi.org/10.2174/0929867321666141011194825</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2174/0929867321666141011194825" target="_blank" >10.2174/0929867321666141011194825</a>

Result language
angličtina
Original language name
Recent Advances in Design of Potential Quinoxaline Anti-Infectives
Original language description
Antimicrobial diazanaphthalenes are indispensable in the treatment of various infections. The quinoxaline scaffold possesses unique physicochemical properties and provides a possibility of a great number of targeted modifications. Quinoxaline-based compounds have a wide range of promising biological properties; therefore a special attention is paid to them for research and designing of new drugs. In fact, quinoxaline can be considered as a privileged structure. The scaffold can be easily and rapidly constructed, which emphasizes the significance of this favourable structure. The review is focused on recently reported potential antibacterial, antimycobacterial, antifungal and antiprotozoal agents derived from the quinoxaline scaffold, their mechanism ofaction and structure-activity relationships. A brief classification of synthetic pathways of quinoxaline derivatives is provided too.
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
—

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)