Anticholinesterase, antioxidant activity and phytochemical investigation into aqueous extracts from five species of Agrimonia genus.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F16%3A43873474" target="_blank" >RIV/62157124:16370/16:43873474 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1080/14786419.2015.1043552" target="_blank" >http://dx.doi.org/10.1080/14786419.2015.1043552</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/14786419.2015.1043552" target="_blank" >10.1080/14786419.2015.1043552</a>
Alternative languages
Result language
angličtina
Original language name
Anticholinesterase, antioxidant activity and phytochemical investigation into aqueous extracts from five species of Agrimonia genus.
Original language description
Aqueous extracts of aerial flowering parts of five Agrimonia species (Rosaceae): Agrimonia coreana Nakai, Agrimonia japonica (Miq.) Koidz, Agrimonia procera Wallr., Agrimonia eupatoria L. and Agrimonia leucantha Kunze were investigated on their antioxidant activity, measured using five different methods; the best was the extract from A. procera with IC50 values from 6 to 29 ?g/mL. All the extracts displayed inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) at the tested concentration of 100 ?g/mL. We found the highest inhibition of cholinesterase in the extract of A. japonica with inhibition 70.4% for AChE and 79.8% for BuChE. These findings are statistically significant in comparison with those of other extracts (p < 0.001). The phytochemical analyses showed that the antioxidant activity of Agrimonia extracts can be affected especially by hexahydroxydiphenoyl (HHDP)-glucose and quercetin glycosides, and inhibition of cholinesterases by apigenin, luteolin and quercetin glycosides.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Natural product research
ISSN
1478-6419
e-ISSN
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Volume of the periodical
30
Issue of the periodical within the volume
10
Country of publishing house
GB - UNITED KINGDOM
Number of pages
4
Pages from-to
1174-1177
UT code for WoS article
000373635600012
EID of the result in the Scopus database
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