Atherogenic index of plasma is positively associated with the risk of all-cause death in elderly women A 10-year follow-up

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F17%3A43875999" target="_blank" >RIV/62157124:16370/17:43875999 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/17:00098763 RIV/00159816:_____/17:00067715

Result on the web

<a href="http://dx.doi.org/10.1007/s00508-017-1264-1" target="_blank" >http://dx.doi.org/10.1007/s00508-017-1264-1</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00508-017-1264-1" target="_blank" >10.1007/s00508-017-1264-1</a>

Result language

angličtina

Original language name

Atherogenic index of plasma is positively associated with the risk of all-cause death in elderly women A 10-year follow-up

Original language description

Background The blood concentrations of total cholesterol and low-density lipoprotein (LDL) do not predict survival in patients older than 60 years. The atherogenic index of plasma (AIP) is a logarithm of the triacylglycerol to high-density lipoprotein (HDL) ratio and a surrogate for the concentration of small dense LDL. It might be a better reflection of the risk of all-cause death in elderly patients. Methods We conducted a prospective observational study of patients with arterial hypertension older than 60 years. The concentrations of total cholesterol, LDL, HDL and triacylglycerol were measured at the time of the recruitment and the patients were observed for 10 years. Cox regression analysis was performed to assess the effects of lipoproteins and AIP on survival. Results A total of 500 patients were recruited and 473 of them (226 men, 247 women) either died or successfully completed the 10-year follow-up and were included in the analysis. The AIP was positively associated, while HDL concentration was negatively associated with the risk of all-cause death adjusted for age, smoking habits, statin use, history of diabetes mellitus, myocardial infarction, stroke and peripheral artery occlusive disease (PAOD) in elderly women but not in men. The LDL, total cholesterol, triacylglycerol and non-HDL concentrations were not associated with the risk of death in both sexes. Conclusions The AIP is positively associated with the risk of all-cause death in elderly women with arterial hypertension independent of age, smoking habits, statin therapy and comorbidities.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30104 - Pharmacology and pharmacy

Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Wiener Klinische Wochenschrift

ISSN

0043-5325

e-ISSN

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Volume of the periodical

129

Issue of the periodical within the volume

21-22

Country of publishing house

AT - AUSTRIA

Number of pages

6

Pages from-to

793-798

UT code for WoS article

000414784300003

EID of the result in the Scopus database

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