Perspectives and challenges of antioxidant therapy for atrial fibrillation

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F17%3A43876022" target="_blank" >RIV/62157124:16370/17:43876022 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/17:00098629
Result on the web
<a href="http://dx.doi.org/10.1007/s00210-016-1320-9" target="_blank" >http://dx.doi.org/10.1007/s00210-016-1320-9</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00210-016-1320-9" target="_blank" >10.1007/s00210-016-1320-9</a>

Result language
angličtina
Original language name
Perspectives and challenges of antioxidant therapy for atrial fibrillation
Original language description
Atrial fibrillation (AF) is the most common sustained arrhythmia associated with significant morbidity and mortality. The mechanisms underlying the pathogenesis of AF are poorly understood, although electrophysiological remodeling has been described as an important initiating step. There is growing evidence that oxidative stress is involved in the pathogenesis of AF. Many known triggers of oxidative stress, such as age, diabetes, smoking, and inflammation, are linked with an increased risk of arrhythmia. Numerous preclinical studies and clinical trials reported the importance of antioxidant therapy in the prevention of AF, using vitamins C and E, polyunsaturated fatty acids, statins, or nitric oxide donors. The aim of our work is to give a current overview and analysis of opportunities, challenges, and benefits of antioxidant therapy in AF.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30104 - Pharmacology and pharmacy

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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