The biophysical study of newly designed fullerenedoxorubicin nanotransporter conjugates for targeted breast cancer therapy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F18%3A43877000" target="_blank" >RIV/62157124:16370/18:43877000 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
The biophysical study of newly designed fullerenedoxorubicin nanotransporter conjugates for targeted breast cancer therapy
Original language description
A detailed interaction study of chitosan nanotransporter, zinc ions and TPP has been performed. The Zn2+ concentration shows the strong effect on crosslinking and coiling of CS NPs with the result of better nanoparticle stabilization confirmed by ninhydrin assay and electrochemical determination. The entrapment efficiency for doxorubicin of designed CS NPs was 20%.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
30104 - Pharmacology and pharmacy
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů