Determination of antitumor activity of biosynthesized silver nanoparticles

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F18%3A43877194" target="_blank" >RIV/62157124:16370/18:43877194 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Determination of antitumor activity of biosynthesized silver nanoparticles
Original language description
Aim of this work was to monitor the effect of AgNPs prepared by green synthesis (AgNPsGS) on the MCF-7 breast tumor cell line and the H1299 lung tumor cell line and to compare this effect with AgNPs prepared by chemical synthesis (AgNPsCHS).The AgNPsGS were at a concentration of 160 ?M Ag+ ions cytotoxic for the both MCF-7 and HCT 116 tumor cell lines and reduced the metabolic activity of the cells to 0-20%. At a concentration of 80 ?M of Ag+ ions, cellular metabolic activity decreased to 0-60%. In contrast, AgNPsCHS were effective up to a much higher concentration of Ag+ ions (16 mM) and exhibited a lower inhibitory effect on both the MCF-7 and HCT 116 cell lines than the green synthesis nanoparticles.
Czech name
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Czech description
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Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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