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Indol-2-carboxylic acid esters containing N-phenylpiperazine moiety - synthesis anticholinergic activity

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F19%3A43878134" target="_blank" >RIV/62157124:16370/19:43878134 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Indol-2-carboxylic acid esters containing N-phenylpiperazine moiety - synthesis anticholinergic activity

  • Original language description

    Final 18 indolylcarbonyloxyaminopropanols in the form of dihydrochlorides, fumarates and quaternary ammonium salts were prepared, using various optimizing ways to synthesize the substances. The compounds were subjected to selected anticholinergic activity evaluation, and thus the impacts of their chemical structure on their biological effect were discussed.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    30107 - Medicinal chemistry

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů