Indol-2-carboxylic acid esters containing N-phenylpiperazine moiety - synthesis anticholinergic activity
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F19%3A43878134" target="_blank" >RIV/62157124:16370/19:43878134 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Indol-2-carboxylic acid esters containing N-phenylpiperazine moiety - synthesis anticholinergic activity
Original language description
Final 18 indolylcarbonyloxyaminopropanols in the form of dihydrochlorides, fumarates and quaternary ammonium salts were prepared, using various optimizing ways to synthesize the substances. The compounds were subjected to selected anticholinergic activity evaluation, and thus the impacts of their chemical structure on their biological effect were discussed.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
30107 - Medicinal chemistry
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů