Exploration of Autoimmune Diseases Using Multi-Agent Systems

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18450%2F16%3A50004913" target="_blank" >RIV/62690094:18450/16:50004913 - isvavai.cz</a>
Result on the web
<a href="http://link.springer.com/book/10.1007/978-3-319-45246-3/page/2" target="_blank" >http://link.springer.com/book/10.1007/978-3-319-45246-3/page/2</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-319-45246-3_27" target="_blank" >10.1007/978-3-319-45246-3_27</a>

Result language
angličtina
Original language name
Exploration of Autoimmune Diseases Using Multi-Agent Systems
Original language description
Autoimmune disease is a group of pathological events identified by abnormal reactions of the immune system against self-structures of the organism. Pathogenesis of autoimmune diseases is multi-factorial. Genetics, infections, and environmental factors can support the progress of the autoimmunity. We investigated this mechanism using in vivo or in vitro approaches. Main aim of this manuscript is to explore the autoimmunity with in-silico approach - multi-agent systems. The preliminary research finds out which results can be acquired using factual data applied for building the multi-agent-based model. Preliminary computational model integrates one of the common aspects of autoimmune diseases - abnormal behaviour of B-cells during their organogenesis.
Czech name
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Czech description
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Project
<a href="/en/project/GA14-02424S" target="_blank" >GA14-02424S: Methods of operations research for decision support under uncertainty</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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