Onset of mortality increase with age and age trajectories of mortality from all diseases in the four Nordic countries

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18450%2F17%3A50005585" target="_blank" >RIV/62690094:18450/17:50005585 - isvavai.cz</a>

Result on the web

<a href="https://www.dovepress.com/onset-of-mortality-increase-with-age-and-age-trajectories-of-mortality-peer-reviewed-article-CIA" target="_blank" >https://www.dovepress.com/onset-of-mortality-increase-with-age-and-age-trajectories-of-mortality-peer-reviewed-article-CIA</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2147/CIA.S119327" target="_blank" >10.2147/CIA.S119327</a>

Result language

angličtina

Original language name

Onset of mortality increase with age and age trajectories of mortality from all diseases in the four Nordic countries

Original language description

Background: The answer to the question &quot;At what age does aging begin?&quot; is tightly related to the question &quot;Where is the onset of mortality increase with age?&quot; Age affects mortality rates from all diseases differently than it affects mortality rates from nonbiological causes. Mortality increase with age in adult populations has been modeled by many authors, and little attention has been given to mortality decrease with age after birth. Materials and methods: Nonbiological causes are excluded, and the category &quot;all diseases&quot; is studied. It is analyzed in Denmark, Finland, Norway, and Sweden during the period 1994-2011, and all possible models are screened. Age trajectories of mortality are analyzed separately: before the age category where mortality reaches its minimal value and after the age category. Results: Resulting age trajectories from all diseases showed a strong minimum, which was hidden in total mortality. The inverse proportion between mortality and age fitted in 54 of 58 cases before mortality minimum. The Gompertz model with two parameters fitted as mortality increased with age in 17 of 58 cases after mortality minimum, and the Gompertz model with a small positive quadratic term fitted data in the remaining 41 cases. The mean age where mortality reached minimal value was 8 (95% confidence interval 7.05-8.95) years. The figures depict an age where the human population has a minimal risk of death from biological causes. Conclusion: Inverse proportion and the Gompertz model fitted data on both sides of the mortality minimum, and three parameters determined the shape of the age-mortality trajectory. Life expectancy should be determined by the two standard Gompertz parameters and also by the single parameter in the model c/x. All-disease mortality represents an alternative tool to study the impact of age. All results are based on published data.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10101 - Pure mathematics

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Clinical interventions in aging

ISSN

1178-1998

e-ISSN

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Volume of the periodical

12

Issue of the periodical within the volume

1

Country of publishing house

NZ - NEW ZEALAND

Number of pages

13

Pages from-to

161-173

UT code for WoS article

000392326100001

EID of the result in the Scopus database

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