THE EFFICACY OF SELECTED BARIATRIC SURGERY METHODS ON LIPID AND GLUCOSE METABOLISM: A RETROSPECTIVE 12-MONTH STUDY

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18450%2F18%3A50014448" target="_blank" >RIV/62690094:18450/18:50014448 - isvavai.cz</a>

Alternative codes found

RIV/61988987:17110/18:A1901VY3 RIV/00179906:_____/18:10382629

Result on the web

<a href="http://www.naun.org/main/NAUN/computers/2016/a142007-164.pdf" target="_blank" >http://www.naun.org/main/NAUN/computers/2016/a142007-164.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.21101/cejph.a4637" target="_blank" >10.21101/cejph.a4637</a>

Result language

angličtina

Original language name

THE EFFICACY OF SELECTED BARIATRIC SURGERY METHODS ON LIPID AND GLUCOSE METABOLISM: A RETROSPECTIVE 12-MONTH STUDY

Original language description

Objective: Approximately 25% of the Czech population is currently obese. Obesity rates are expected to increase in the future. Obesity not only raises the risk of health complications for individuals, but increasing rates also represent a significant and steadily growing economic burden for healthcare systems and society as a whole. The aim of this study was to evaluate the therapeutic efficacy of three methods of bariatric surgery: laparoscopic greater curve plication (LGCP), laparoscopic sleeve gastrectomy (LSG), and Roux-en-Y gastric bypass (RYBG) in patients with type 2 diabetes mellitus (DM). This study examined the influence of bariatric surgery on body weight and BMI, changes in serum glucose and markers of lipid metabolism. Methods: This study evaluated outcomes in 74 patients with type 2 DM who underwent LGCP, LSG or RYGB. Patient selection followed guidelines of the International Federation for the Surgery of Obesity, i.e. BMI &gt;= 40 kg/m(2) or BMI &gt;= 35 kg/m(2) with associated comorbidities or BMI &lt;35 kg/m(2). For each of the procedures, the hypotheses were tested with the Bonferroni method. Results: Statistically significant weight loss, 20.2 +/- 9.3 kg on average, occurred by 12 months after surgery, with maximum weight reduction of 38 kg. Over the 12-month period, average fasting glycaemia decreased by 2.58 mmol/L after LGCP, by 2.01 mmol/L after LSG, and by 4.64 mmol/L after RYGB. Triacylglycerol (TGC) values decreased significantly with all procedures. The mean decrease was 1.35 mmol/L after LGCP and 1.06 mmol/L after LSG. The greatest TGC concentration decrease, 1.92 mmol/L, occurred after RYGB. Average concentrations decreased below 1.7 mmol/L. There was a statistically significant difference in body weight and BMI reduction between LGCP and LSG groups, as well as between LGCP and RYGB groups. A significant difference in the glucose decrease was observed between the LSG and RYGB groups, which can be explained by the fact that glycaemia and HbA1c levels were different between these groups prior to surgery. Conclusions: The best results from the carbohydrate metabolism point reached the malabsorption method RYGB. However, the other two restrictive methods also achieved very good results. In particular, the LGCP method has not only the effect on weight reduction but also on metabolic functions and consequently points to potential healthcare expenditure savings.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

50202 - Applied Economics, Econometrics

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Central European journal of public health

ISSN

1210-7778

e-ISSN

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Volume of the periodical

26

Issue of the periodical within the volume

1

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

5

Pages from-to

49-53

UT code for WoS article

000432850200009

EID of the result in the Scopus database

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