Spatially selective modification of PLLA surface: From hydrophobic to hydrophilic or to repellent

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18470%2F17%3A50005591" target="_blank" >RIV/62690094:18470/17:50005591 - isvavai.cz</a>

Alternative codes found

RIV/44555601:13440/17:43892925 RIV/00179906:_____/17:10337254 RIV/60461373:22310/17:43914144

Result on the web

<a href="http://www.sciencedirect.com/science/article/pii/S0169433216324308" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0169433216324308</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.apsusc.2016.11.062" target="_blank" >10.1016/j.apsusc.2016.11.062</a>

Result language

angličtina

Original language name

Spatially selective modification of PLLA surface: From hydrophobic to hydrophilic or to repellent

Original language description

A universal approach to controlled surface modification of polylactic acid (PLLA) films using diazonium chemistry was proposed. The multistep procedure includes surface activation of PLLA by argon plasma treatment and chemical activation of arenediazonium tosylates by NaBH4. The surface of PLLA film was grafted withdifferentfunctional organic groups (OFGs), changing the PLLAsurface properties (wettability, morphology, zeta potential, chemical composition, and mechanical response). Three approaches of OFG grafting were examined: (i) plasma treatment following by PLLA immersion into diazonium salt aqueous solution; (ii) grafting of PLLA surface through the reaction with chemically created aryl radicals; (iii) mutual combination of both methods The best results were achieved in the last case, where the previous plasma treatment was combined with further reaction of PLLA surface with generated aryl radicals. Using this method PLLA surface was successfully grafted with amino, carboxyl, aliphatic and fluorinated OFGs. Further investigation of surface properties from potential biological and medical points of view was performed using zeta potential, biodegradation and biofouling tests. It was shown that proposed technique allows preparation of biorepellent or bioabsorptive surfaces, tuning of PLLA biodegradation rate and nanomechanical properties, as well as the introduction of inverse properties (such as hydrophilic and hydrophobic) on both sides of PLLA films.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30104 - Pharmacology and pharmacy

Project

<a href="/en/project/NV15-33459A" target="_blank" >NV15-33459A: Biomedical photonic devices for advanced medicinal diagnostics and therapy</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Applied surface science

ISSN

0169-4332

e-ISSN

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Volume of the periodical

397

Issue of the periodical within the volume

March

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

9

Pages from-to

226-234

UT code for WoS article

000393001600029

EID of the result in the Scopus database

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