Jatropha gossypiifolia L. and its biologically active metabolites: A mini review
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18470%2F19%3A50015505" target="_blank" >RIV/62690094:18470/19:50015505 - isvavai.cz</a>
Alternative codes found
RIV/60076658:12110/19:43899107 RIV/00179906:_____/19:10393183
Result on the web
<a href="https://www.sciencedirect.com/science/article/abs/pii/S0378874118319780" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S0378874118319780</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jep.2019.01.022" target="_blank" >10.1016/j.jep.2019.01.022</a>
Alternative languages
Result language
angličtina
Original language name
Jatropha gossypiifolia L. and its biologically active metabolites: A mini review
Original language description
Ethnopharmacological relevance: Jatropha gossypiifolia L. (Euphorbiaceae) is popularly known as bellyache bush or black physic nut and is widely used in local / traditional medicine due to the various biological activities attributed to its different parts, including its leaves, roots, and latex. Aim of the study: In this review, we aim to update and discuss the chemistry, specific pharmacology, and toxicological activities of Jatropha gossypiifolia and its bioactive metabolites. Materials and methods: The Web of Science, PubMed, Google Scholar, SciFinder, Cochrane Library, Scopus, and Science Direct databases were searched with the name "Jatropha gossypiifolia" and the term "bioactive metabolites". All studies on the chemistry, pharmacology, and toxicology of the plant up to December 2018 were included in this review. Results: Jatropha gossypiifolia leaves are considered to have anti-inflammatory, antimicrobial and insecticidal properties. The root and stem have anti-inflammatory and antimicrobial properties. The seeds and fruits can be used against influenza and as a sedative, analgesic or anti-diarrheal agents. The latex is bactericidal and molluscicidal. Topical application of latex is used to treat wounds and bites of venomous animals. The diluted form is usually used for the treatment of diarrhoea by indigenous peoples. Conclusions: The main pharmacological activities of Jatropha gossypiifolia include anti-inflammatory, antineoplastic, antimicrobial, antioxidant, and anticholinesterase, and antihypertensive activities. Species of Jatropha are notably known for their toxic potential, and their toxicity is primarily related to the latex and seed contents. However, the potential mechanisms of these pharmacological activities have not been fully explored. We hope this review will help to further inform the potential utilization of Jatropha gossypiifolia in complementary and alternative medicine.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30104 - Pharmacology and pharmacy
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
JOURNAL OF ETHNOPHARMACOLOGY
ISSN
0378-8741
e-ISSN
—
Volume of the periodical
234
Issue of the periodical within the volume
April
Country of publishing house
IE - IRELAND
Number of pages
7
Pages from-to
197-203
UT code for WoS article
000461404300019
EID of the result in the Scopus database
2-s2.0-85061375873