Novel crispr–cas systems: An updated review of the current achievements, applications, and future research perspectives

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18470%2F21%3A50017963" target="_blank" >RIV/62690094:18470/21:50017963 - isvavai.cz</a>

Result on the web

<a href="https://www.mdpi.com/1422-0067/22/7/3327" target="_blank" >https://www.mdpi.com/1422-0067/22/7/3327</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/ijms22073327" target="_blank" >10.3390/ijms22073327</a>

Result language

angličtina

Original language name

Novel crispr–cas systems: An updated review of the current achievements, applications, and future research perspectives

Original language description

According to Darwin’s theory, endless evolution leads to a revolution. One such example is the Clustered Regularly Interspaced Palindromic Repeats (CRISPR)–Cas system, an adaptive immunity system in most archaea and many bacteria. Gene editing technology possesses a crucial potential to dramatically impact miscellaneous areas of life, and CRISPR–Cas represents the most suitable strategy. The system has ignited a revolution in the field of genetic engineering. The ease, precision, affordability of this system is akin to a Midas touch for researchers editing genomes. Undoubtedly, the applications of this system are endless. The CRISPR–Cas system is extensively employed in the treatment of infectious and genetic diseases, in metabolic disorders, in curing cancer, in developing sustainable methods for fuel production and chemicals, in improving the quality and quantity of food crops, and thus in catering to global food demands. Future applications of CRISPR– Cas will provide benefits for everyone and will save countless lives. The technology is evolving rapidly; therefore, an overview of continuous improvement is important. In this review, we aim to elucidate the current state of the CRISPR–Cas revolution in a tailor‐made format from its discovery to exciting breakthroughs at the application level and further upcoming trends related to opportunities and challenges including ethical concerns. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10402 - Inorganic and nuclear chemistry

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International journal of molecular sciences

ISSN

1422-0067

e-ISSN

—

Volume of the periodical

22

Issue of the periodical within the volume

7

Country of publishing house

CH - SWITZERLAND

Number of pages

42

Pages from-to

"Article number 3327"

UT code for WoS article

000638625400001

EID of the result in the Scopus database

2-s2.0-85102945416