Hybrid materials based on magnetic iron oxides with benzothiazole derivatives: A plausible potential spectroscopy probe
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18470%2F21%3A50018006" target="_blank" >RIV/62690094:18470/21:50018006 - isvavai.cz</a>
Result on the web
<a href="https://www.mdpi.com/1422-0067/22/8/3980" target="_blank" >https://www.mdpi.com/1422-0067/22/8/3980</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/ijms22083980" target="_blank" >10.3390/ijms22083980</a>
Alternative languages
Result language
angličtina
Original language name
Hybrid materials based on magnetic iron oxides with benzothiazole derivatives: A plausible potential spectroscopy probe
Original language description
Rare diseases affect a small part of the population, and the most affected are children. Because of the low availability of patients for testing, the pharmaceutical industry cannot develop drugs for the diagnosis of many of these orphan diseases. In this sense, the use of benzothiazole compounds that are highly selective and can act as spectroscopy probes, especially the compound 2-(4′-aminophenyl)benzothiazole (ABT), has been highlighted. This article reports the design of potential contrast agents based on ABT and iron to develop a new material with an efficient mechanism to raise the relaxation rate, facilitating diagnosis. The ABT/δ-FeOOH hybrid material was prepared by grafting (N-(4’-aminophenyl) benzothiazole-2-bromoacetamide) on the surface of the iron oxyhydroxide particles. FTIR spectra confirmed the material formations of the hybrid material ABT/δ-FeOOH. SEM analysis checked the covering of nanoflakes’ surfaces in relation to the morphology of the samples. The theoretical calculations test a better binding mode of compound with iron oxyhydroxide. Theoretical findings show the radical capture mechanism in the stabilization of this new material. In this context, Fe3+ ions are an electron acceptor from the organic phase. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10402 - Inorganic and nuclear chemistry
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International journal of molecular sciences
ISSN
1422-0067
e-ISSN
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Volume of the periodical
22
Issue of the periodical within the volume
8
Country of publishing house
CH - SWITZERLAND
Number of pages
12
Pages from-to
"Article number 3980"
UT code for WoS article
000644386100001
EID of the result in the Scopus database
2-s2.0-85103908470