Bacillus amyloliquefaciens B10 inhibits aflatoxin B1-induced cecal inflammation in mice by regulating their intestinal flora

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18470%2F21%3A50018210" target="_blank" >RIV/62690094:18470/21:50018210 - isvavai.cz</a>

Alternative codes found

RIV/00179906:_____/21:10432443

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S0278691521004713?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0278691521004713?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.fct.2021.112438" target="_blank" >10.1016/j.fct.2021.112438</a>

Result language

angličtina

Original language name

Bacillus amyloliquefaciens B10 inhibits aflatoxin B1-induced cecal inflammation in mice by regulating their intestinal flora

Original language description

Aflatoxin B1 is a mycotoxin that widely exists in feed and has a great impact on human and animal health. This study aimed to examine whether Bacillus amyloliquefaciens B10 protected against aflatoxin B1-induced cecal inflammation in mice. It was found that Bacillus amyloliquefaciens B10 could significantly improve the effects of AFB1 on body weight and intestinal inflammation of mice and enhance the expression of tight-junction protein. Compared with the CON group, the combination of AFB1 and B10 significantly increased the abundance of Actinobacteria and Bacilli in a collaborative manner, and significantly reduced the abundance of Ruminococcae, Lactobacillaceae and Clostridia. Meanwhile, the results showed that the abundance of Bacterides and Bacterdia in AFB1 + B10 group was significantly lower than that of AFB1 group, and the Firmicutes increased significantly. Bacillus amyloliquefaciens B10 can be used as a feed additive and alleviate cecal inflammation induced by AFB1 in mice by regulating intestinal flora. © 2021 Elsevier Ltd

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30108 - Toxicology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Food and chemical toxicology

ISSN

0278-6915

e-ISSN

—

Volume of the periodical

156

Issue of the periodical within the volume

October

Country of publishing house

GB - UNITED KINGDOM

Number of pages

11

Pages from-to

"Article number: 112438"

UT code for WoS article

000698511700002

EID of the result in the Scopus database

2-s2.0-85111176635