Painful or painless lower limb dysesthesias are highly predictive of peripheral neuropathy: Comparison of different diagnostic modalities

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F09%3A%230000803" target="_blank" >RIV/65269705:_____/09:#0000803 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Painful or painless lower limb dysesthesias are highly predictive of peripheral neuropathy: Comparison of different diagnostic modalities

Original language description

42 patients were recruited prospectively and underwent a clinical examination,nerve conduction studies, quantitative sensory testing(QST)and skin biopsy at the dorsum of the foot.All patients had a correlate for their dysesthesias in at least one diagnostic modality.Most patients(>90%)had signs of small fiber loss or dysfunction.In about half of all patients large fibers were also affected.Nerve conduction studies were abnormal in 23/42 patients(54.8%).Cold or warm detection thresholds in QST were abnormal in 15/42(35.7%)patients.Decreased intraepidermal nerve fiber density(IENFD)was found in 37 patients(88.1%)including some patients with normal QST findings.Nearly all patients with pathological QST had a reduced IENFD,indicating a high positive predictive value(93%)of QST in screening for reduced IENFD as correlate for neuropathy.Therefore in all patients with lower limb dysesthesias of unknown origin,the non-invasive methods of NCS and QST should be used and potentially complemented

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European Journal of Pain

ISSN

1090-3801

e-ISSN

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Volume of the periodical

13

Issue of the periodical within the volume

7

Country of publishing house

GB - UNITED KINGDOM

Number of pages

8

Pages from-to

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UT code for WoS article

000268384500006

EID of the result in the Scopus database

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