The treatment of HSV1 ocular infections using quantitative real-time PCR results

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F10%3A%230000981" target="_blank" >RIV/65269705:_____/10:#0000981 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/12:00061211

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

The treatment of HSV1 ocular infections using quantitative real-time PCR results

Original language description

Herpes stromal keratitis is a serious condition and the most frequent cause of unilateral blindness. The real-time PCR is an accurate and fast diagnostic method for an analysis of infectious agents causing keratitis and keratouveitis. The aim of the study was to assess the relationship between clinical symptoms, treatment efficacy monitoring and viral quantity in corneal swabs determined by quantitative real-time PCR method. The real-time PCR method was used as well for the detection of other viral eyepathogens. Methods: a total of 212 patients (136 male and 76 female) suspect of having herpes simplex virus (HSV) keratitis or keratouveitis were included in the study. The detection and quantitative analysis of the viral DNA was performed using the EliGene HSV1 RT kit and the result was correlated with the clinical picture of the disease.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FF - ENT (ie. ear, nose, throat), ophthalmology, dentistry

OECD FORD branch

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Project

<a href="/en/project/NR8507" target="_blank" >NR8507: DNA diagnostics of bacterial and viral infections of the cornea</a><br>

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta ophthalmologica

ISSN

1755-375X

e-ISSN

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Volume of the periodical

88

Issue of the periodical within the volume

3

Country of publishing house

US - UNITED STATES

Number of pages

5

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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